This dosing guide can help you determine the recommended weight-based per meal dosing for your patients with exocrine pancreatic insufficiency (EPI) due to cystic fibrosis.
CREON® is indicated for the treatment of exocrine pancreatic insufficiency due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions.1
Dosage recommendations for pancreatic enzyme replacement therapy were published following the Cystic Fibrosis Foundation Consensus Conferences.
Patients should be advised that the total daily dose should not exceed 10,000 lipase units/kg body weight/day unless clinically indicated. CREON dosage should be individualized and adjusted based on the clinical symptoms, degree of steatorrhea present, and the fat content of the diet. Instruct patients and caregivers that CREON should only be taken as directed by their healthcare professional. CREON should always be taken with food. CREON should not be crushed or chewed. If a CREON dose is missed, the next dose should be taken with the next meal. Doses should not be doubled. Usually, half of the prescribed CREON dose for an individualized full meal should be given with each snack.
CREON® (pancrelipase) Delayed-Release Capsules is a pancrelipase which is a combination of porcine-derived lipases, proteases, and amylases indicated for the treatment of exocrine pancreatic insufficiency due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions.
See CREON dosing guidelines.
Support for you and your patients in managing EPI and CF.
Make sure your patients receive the CREON co-pay card.