What is EPI
EPI is a condition that occurs when the pancreas doesn’t make enough digestive enzymes.
CREON (pancrelipase) is a prespcription medicine used to treat EPI (exocrine pancreatic insufficiency). EPI is a condition where the pancreas doesn't release enough digestive enzymes to break down food. CREON treats EPI due to cystic fibrosis, chronic pancreatitis and pancreatectomy by replenishing enzymes you are missing.
Get tools and tips to help you start and stay on track with your CREON treatment plan.
Review facts about EPI, discover how CREON works, and more, in short educational videos.
CREON's patient support programs provide you with:
*Eligibility: Available to patients with commercial prescription insurance coverage for CREON® (pancrelipase) who meet eligibility criteria. Neither co-pay assistance nor multivitamins/nutritional supplements are available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offers subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit
or call 1-844-662-7366 for additional information. For full Terms and Conditions for CREON CF patients, visit
or call 1-855-227-3493 for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit
CREON® (pancrelipase) is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.
Refer to the CREON Medication Guide and full Prescribing Information every time you refill your prescription because information may change. Tell your healthcare provider if you have any symptom or side effect that bothers you or that does not go away.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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