Fibrosing colonopathy has been reported in patients with cystic fibrosis taking high dose pancreatic enzyme replacement therapy. Use caution when prescribing CREON to patients with gout, renal impairment, or hyperuricemia, and in patients with pork allergies. There is a theoretical risk of viral transmission with pancreatic enzyme products including CREON. CREON should always be taken with food. CREON should not be crushed or chewed.
EPI is a condition that affects your pancreas. Your pancreas makes natural proteins called enzymes that help break down food so it can be absorbed by the body. If you have EPI, you do not produce and/or secrete enough pancreatic enzymes to break down food. Learn more about EPI.
Pancreatectomy is the surgical removal of the pancreas. There are different types. A complete pancreatectomy is removal of the entire pancreas and parts of surrounding organs. A partial pancreatectomy is removal of part of the pancreas and sometimes parts of surrounding organs. If you have had some form of partial pancreatectomy, you may experience diabetes or EPI. If you have had a complete pancreatectomy, it will result in diabetes and EPI.
Chronic pancreatitis is inflammation of the pancreas that does not heal or improve, gets worse over time, and may lead to permanent damage. The amount of pancreatic tissue that is destroyed can vary. Many patients with CP also have EPI because their pancreas has become so damaged that it can no longer produce enough of the enzymes necessary to properly digest food.
CF is a genetic disease that causes the body to produce thick, sticky mucus. This mucus clogs the lungs and leads to infections in the lungs. The mucus also affects the digestive system by clogging the pancreas. Most people with CF also have exocrine pancreatic insufficiency (EPI).
CREON is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.
CREON does not cure exocrine pancreatic insufficiency. CREON contains digestive enzymes that help break down fats, proteins, and carbohydrates. Learn more about CREON.
Take CREON exactly as instructed by your healthcare professional. Always take CREON with a meal or snack and enough liquid to swallow CREON completely. Do not crush or chew CREON capsules or its contents, and do not hold the capsule or capsule contents in your mouth. Crushing, chewing or holding the CREON capsules in your mouth may cause irritation in your mouth or change the way CREON works in your body. Get more information here.
The most common side effects include: increased (hyperglycemia) or decreased (hypoglycemia) blood sugars, pain in your stomach area (abdominal area), frequent or abnormal bowel movements, gas, vomiting, dizziness or sore throat and cough. Always check with your healthcare professional and carefully discuss the risks and benefits before taking CREON.
CREON is often covered by insurance. Contact your insurance provider to find out if CREON is covered under your particular policy. Learn about the CREON Co-Pay Assistance program.
Yes. AbbVie Inc. offers a Patient Assistance Program (PAP) through which certain patients can obtain CREON at no cost if they meet financial eligibility criteria. Physicians apply for the PAP program on the patient's behalf by submitting a completed application.
Yes. The program is called CFCareForward.
No. You should not switch CREON with any other pancreatic enzyme product without first talking to your doctor. If you have any questions about your prescription, talk to your healthcare professional. Learn more about CREON.
CREON® is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.
CREON replaces pancreatic enzymes, helping you digest nutrients.
Learn why a well-balanced diet is important for patients with EPI due to CF.
Activate your CREON
You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you cannot afford your medication, contact: www.pparx.org for assistance.