Pancreatic enzyme replacement therapies (PERTs) like CREON help patients with exocrine pancreatic insufficiency (EPI) break down food and digest nutrients by replacing the pancreatic enzymes made by a healthy pancreas, which are lipase, protease and amylase.
As shown below, the CREON capsules mix with food in the stomach. The mixture travels to the small intestine, where the pancreatic enzymes in CREON are released and digest the nutrients in food.
Click the numbers on the image to see how CREON works:
Capsules shown are not actual size and do not represent exact color shade.
In order for CREON to work, it must be taken with food. CREON should not be crushed or chewed. Crushing, chewing or holding the capsules or capsule contents in your mouth may cause irritation in your mouth or change the way CREON works in your body. Always take CREON exactly as prescribed by your doctor.
CREON is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.
Get instructions for taking CREON.
Activate your CREON
Tell us how you are managing your EPI due to CF with CREON.
You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you cannot afford your medication, contact: www.pparx.org or call the toll-free phone number (1-888-4PPA-NOW) for assistance.