CREON Patient Support
and Resources

Helping your patients with EPI get the support they need

CREON provides resources and tools to help support your patients manage exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF), chronic pancreatitis (CP), pancreatectomy, or other conditions.

CREON® (pancrelipase) Educational Videos

The Bite-sized education series contains videos that are designed to help patients learn the basics about EPI and CREON


CREON® (pancrelipase) Patient Support Videos

CREON patient videos offer experiences and tips from real patients who are living with EPI


CREON® (pancrelipase) Treatment Tracker

The CREON Treatment Tracker can help patients follow up and share their progress with you


CREON® (pancrelipase) Doctor Discussion Guide

The Discussion Guide can help patients feel more comfortable discussing their GI symptoms with you

Request patient starter kits, product samples, and more

Request patient starter kits, product samples, and more

Contact a Rep
Use the dosing calculator to help determine the proper dosage of CREON® (pancrelipase)

Determine an appropriate per-meal dose for your patients

Use Dosing Guide
Help your patients learn more about CREON® (pancrelipase) and EPI

Help patients learn
about EPI and CREON

View Patient Videos

Indications and Important
Safety Information

Indications1

CREON® (pancrelipase) Delayed-Release Capsules is a pancrelipase which is a combination of porcine-derived lipases, proteases, and amylases indicated for the treatment of exocrine pancreatic insufficiency due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions.

Important Safety Information

  • Fibrosing colonopathy is associated with high-dose use of pancreatic enzyme replacement in the treatment
    of cystic fibrosis patients. Exercise caution when doses of CREON exceed 2,500 lipase units/kg of body weight
    per meal (or greater than 10,000 lipase units/kg of body weight per day).
  • To avoid irritation of oral mucosa, care should be taken to ensure that CREON is not crushed, chewed, or retained in the mouth. CREON should always be taken with food.
  • Porcine-derived pancreatic enzyme products contain purines. Caution should be exercised when prescribing CREON to patients with gout, renal impairment, or hyperuricemia.
  • There is theoretical risk of viral transmission with all pancreatic enzyme products including CREON.
  • Exercise caution when administering pancrelipase to a patient with a known allergy to proteins of porcine origin.
  • Adverse reactions that occurred in at least 2 cystic fibrosis patients (greater than or equal to 4%) receiving CREON were vomiting, dizziness, and cough.
  • Adverse reactions that occurred in at least 1 chronic pancreatitis or pancreatectomy patient (greater than or equal to 4%) receiving CREON were hyperglycemia, hypoglycemia, abdominal pain, abnormal feces, flatulence, frequent bowel movements, and nasopharyngitis.
  • CREON is not interchangeable with any other pancrelipase product.

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.

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