CREON On Course

Financial assistance programs may offer patients more
affordable treatment

CREON patients pay as little as $5 per month*

Get financial assistance using the CREON® Co-pay Card
  • Eligible CREON patients pay as little as $60 per year
  • CREON On Course can be used for commercial co-pay, co-insurance, and high-deductible plans*
  • Remember to give your patients a CREON co-pay card along with their prescription. If you need CREON co-pay cards for your office, please contact a representative

*Eligibility: Available to patients with commercial prescription insurance coverage for CREON who meet eligibility criteria. Co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the CREON card and patient must call 1-844-ONCREON (662-7366) to stop participation. Patients residing in or receiving treatment in certain states may not be eligible. Patients may not seek reimbursement for value received from CREON On Course from any third-party payers. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance.

AbbVie’s Patient Assistance Foundation provides medicines at no cost to qualified patients. Learn More

Patients who enroll in CREON On Course can get vitamins to supplement a
healthy diet—at no charge

CREON® On Course can provide vitamins to help supplement a healthy diet
  • A variety of multivitamin products in chewable and softgel formulations
  • Suited to individual needs and preferences

†For CREON On Course participants filling CREON prescriptions. Certain restrictions apply. Offer valid within USA only; must be a U.S. citizen or lawful permanent resident. This program is not valid for prescriptions reimbursed under Medicare, Medicaid, or similar federal or state programs. Subject to availability.

Patient education resources and materials

Educate patients about EPI and CREON
  • Contact a representative to order patient starter kits, brochures, and pamphlets for your office staff to distribute to patients.
  • Patients who register for CREON On Course can receive educational emails about: 
    • Savings opportunities
    • Facts about EPI
    • Getting started on CREON
    • Tracking progress
Request patient starter kits, product samples, and more

Request patient starter kits, product samples, and more

Contact a Rep
Use the dosing calculator to help determine the proper dosage of CREON® (pancrelipase)

Determine an appropriate per-meal dose for your patients

Use Dosing Guide

Indications and Important
Safety Information


CREON® (pancrelipase) Delayed-Release Capsules is a pancrelipase which is a combination of porcine-derived lipases, proteases, and amylases indicated for the treatment of exocrine pancreatic insufficiency due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions.

Important Safety Information

  • Fibrosing colonopathy is associated with high-dose use of pancreatic enzyme replacement in the treatment
    of cystic fibrosis patients. Exercise caution when doses of CREON exceed 2,500 lipase units/kg of body weight
    per meal (or greater than 10,000 lipase units/kg of body weight per day).
  • To avoid irritation of oral mucosa, care should be taken to ensure that CREON is not crushed, chewed, or retained in the mouth. CREON should always be taken with food.
  • Porcine-derived pancreatic enzyme products contain purines. Caution should be exercised when prescribing CREON to patients with gout, renal impairment, or hyperuricemia.
  • There is theoretical risk of viral transmission with all pancreatic enzyme products including CREON.
  • Exercise caution when administering pancrelipase to a patient with a known allergy to proteins of porcine origin.
  • Adverse reactions that occurred in at least 2 cystic fibrosis patients (greater than or equal to 4%) receiving CREON were vomiting, dizziness, and cough.
  • Adverse reactions that occurred in at least 1 chronic pancreatitis or pancreatectomy patient (greater than or equal to 4%) receiving CREON were hyperglycemia, hypoglycemia, abdominal pain, abnormal feces, flatulence, frequent bowel movements, and nasopharyngitis.
  • CREON is not interchangeable with any other pancrelipase product.

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.

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