How Children and Adults Take CREON

Take CREON every time you eat

Your doctor prescribed your CREON dose based on a few factors including your body weight and the types of foods you prefer to eat. Usually, patients start out on CREON at the lowest possible dose for their weight. Your doctor may need to adjust your dose depending on your symptoms, how oily and frequent your stools are, and how much fat is in your diet.

It’s very important to take CREON with every meal and snack. Usually, half of the dose your doctor has prescribed for a full meal is what you should take with a snack.

If you forget to take your CREON with a meal or snack, take your next dose the next time you eat. You should never double your CREON dose due to a missed dose.

Key points for adults and
children taking CREON:

Safety Considerations:

CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. Call your healthcare professional right away if you have any unusual or severe stomach pain; frequent or abnormal bowel movements; bloating; trouble passing stool; nausea; vomiting; diarrhea; worsening of gout; painful, swollen joints; trouble with breathing; skin rashes; or swollen lips. When taking CREON, it's important to follow the dosing instructions provided by your healthcare professional. Always take CREON with food. Do not crush or chew CREON capsules or the contents of the capsule. This may cause mouth irritation.

Knowing what foods may cause issues is important

Knowing what foods may cause issues is important

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Learning the basics about CREON® (pancrelipase) is easy

Learning the basics about CREON is easy

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What can I eat with CREON® (pancrelipase)?

What can I eat with CREON?

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Diet & Lifestyle

Uses and Important Safety Information

Uses1

CREON is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.

Important Safety Information

  • CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. The risk of having this condition may be reduced by following the dosing instructions that your doctor gave you.
  • Do not crush or chew CREON capsules or its contents, and do not hold the capsule or capsule contents in your mouth. Crushing, chewing, or holding the CREON capsules in your mouth may cause irritation in your mouth. Talk to your doctor or consult the CREON Medication Guide for how to take CREON if you have trouble swallowing capsules. Always take CREON with a meal or snack and enough liquid to swallow CREON completely. Take CREON exactly as your doctor tells you.
  • Tell your doctor right away if you have unusual or severe: stomach (abdominal) pain, bloating, trouble passing stool, nausea, vomiting, diarrhea, worsening of painful, swollen joints (gout), or allergic reactions including trouble with breathing, skin rashes, or swollen lips.
  • The most common side effects include: increased (hyperglycemia) or decreased (hypoglycemia) blood sugars, pain in your stomach area (abdominal area), frequent or abnormal bowel movements, gas, vomiting, dizziness, or sore throat and cough.
  • CREON and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.

Refer to the CREON Medication Guide and Full Prescribing Information every time you refill your prescription because information may change. Tell your healthcare provider if you have any symptom or side effect that bothers you or that does not go away.

You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you cannot afford your medication, contact www.pparx.org.

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.

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