How CREON Should Be Given to Infants

Giving CREON to your infant up to 12 months old

CREON may be prescribed to infants who have Exocrine Pancreatic Insufficiency (EPI) due to cystic fibrosis (CF). If you’re caring for an infant who needs to take CREON, watch the video for tips on giving enzymes to a baby

Sprinkling instructions:

Image of a capsule being held by two fingers

Hold the capsule upright so that you can see the word CREON on the capsule.

A capsule being twisted open

Carefully twist off the top portion of the capsule.

A capsule's contents being sprinkled onto applesauce

Sprinkle the contents from the capsule directly into your infant’s mouth, or mix the contents in a small amount of room temperature acidic soft food such as applesauce or jarred baby food. Do not mix CREON with formula or bottled breast milk. If you sprinkle CREON on soft food, feed it to your child immediately. Do not store leftover food mixed with CREON.

A mother feeding her child from a bottle

Give your child enough liquid to completely swallow the CREON contents or the CREON and food mixture. Check inside your baby’s mouth that he or she has swallowed all the capsule contents. To avoid irritation, care should be taken to ensure no medicine is left in the mouth. Refer to the CREON Medication Guide for additional instructions.

Capsules shown are not actual size and do not represent actual color shade.

Key points when giving CREON to infants:

Safety Considerations:

CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. Call your healthcare professional right away if you have any unusual or severe stomach pain; frequent or abnormal bowel movements; bloating; trouble passing stool; nausea; vomiting; diarrhea; worsening of gout; painful, swollen joints; trouble with breathing; skin rashes; or swollen lips. When taking CREON, it's important to follow the dosing instructions provided by your healthcare professional. Always take CREON with food. Do not crush or chew CREON capsules or the contents of the capsule. This may cause mouth irritation.

Silhouettes icon

Hear from other people who have EPI

Watch Videos
Learning the basics about CREON® (pancrelipase) is easy

Learning the basics about CREON is easy

Watch Videos
CREON Capsules icon

CREON can help break down food and release nutrients

Find Out How