CREON Videos

We’re committed to helping you learn about EPI and CREON. See below for our Bite-sized Education Series and Patient Video Series.

CREON® (pancrelipase) educational videos

Watch these short videos to learn the basics about exocrine pancreatic insufficiency (EPI) and CREON

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What Is EPI video

What is EPI?

Learn more about the role of the pancreas and how EPI affects digestion.

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CREON & Food video

CREON & food

Learn about when CREON should be taken.

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How CREON Works video

How CREON works

See why CREON needs to be on board with your food.

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Understanding Your CREON Dose video

Understanding your CREON dose

Find out how you and your doctor can work together to find a CREON dose that works for you.

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CREON patient videos

See how real patients, caregivers, and doctors are sharing their experiences with EPI and CREON. Watch the videos below.

Want to share your story? Join the SPEAK network today.

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CREON® (pancrelipase) for those newly diagnosed with EPI Dr. Shahab Mehdizadeh: Helpful tips for newly diagnosed patients

Dr. Mehdizadeh shares helpful tips he gives to newly diagnosed patients.

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Watch how to discuss EPI and your GI symptoms with your doctor Exocrine pancreatic insufficiency (EPI) & GI health: Communicating with your healthcare team

Bryan talks about the importance of discussing GI symptoms with his healthcare team.

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Living with EPI & cystic fibrosis Exocrine pancreatic insufficiency (EPI) and cystic fibrosis (CF)

Sabrina, Jennifer, and Bryan share tips for living with EPI due to CF.

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Caring for a child with exocrine pancreatic insufficiency Caring for a child with exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF)

Jennifer shares insights as a caregiver for her daughter, who has EPI due to CF.

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Tracking treatment can help your doctor see if your therapy is working for you

Tracking treatment can help your doctor
see if your therapy is working for you

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Tell others how you are managing your EPI – register to share your story

Tell others how you are managing your
EPI—register to share your story

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Uses and Important Safety Information


CREON is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.

Important Safety Information

  • CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. The risk of having this condition may be reduced by following the dosing instructions that your doctor gave you.
  • Do not crush or chew CREON capsules or its contents, and do not hold the capsule or capsule contents in your mouth. Crushing, chewing, or holding the CREON capsules in your mouth may cause irritation in your mouth. Talk to your doctor or consult the CREON Medication Guide for how to take CREON if you have trouble swallowing capsules. Always take CREON with a meal or snack and enough liquid to swallow CREON completely. Take CREON exactly as your doctor tells you.
  • Tell your doctor right away if you have unusual or severe: stomach (abdominal) pain, bloating, trouble passing stool, nausea, vomiting, diarrhea, worsening of painful, swollen joints (gout), or allergic reactions including trouble with breathing, skin rashes, or swollen lips.
  • The most common side effects include: increased (hyperglycemia) or decreased (hypoglycemia) blood sugars, pain in your stomach area (abdominal area), frequent or abnormal bowel movements, gas, vomiting, dizziness, or sore throat and cough.
  • CREON and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.

Refer to the CREON Medication Guide and Full Prescribing Information every time you refill your prescription because information may change. Tell your healthcare provider if you have any symptom or side effect that bothers you or that does not go away.

You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

If you cannot afford your medication, contact

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.

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