Stay on Track With
CREON Treatment

Getting off to a good start with CREON

Remember, your CREON prescription dose was written specifically for you by your doctor based on things like your body weight and diet.1

As you start out on CREON, use the CREON Treatment Tracker to chart the first few weeks of CREON therapy. At your next appointment, share the results with your doctor and discuss how your current treatment plan is going. Your doctor may decide to adjust your dose based on your symptoms, your diet, and other factors.

If you’re experiencing any symptoms, call your doctor and schedule a follow-up appointment. Your doctor may need to adjust your CREON dose.

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Simple steps to help keep you on course with treatment

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Take CREON with every meal and snack

Whether it’s a full meal or a snack, take CREON every time you eat. Remember to follow your treatment plan closely and take CREON exactly as prescribed. If you miss a dose, don’t double up; just take it with your next meal or snack.

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Remember to take CREON with you on the go

Plan ahead for when you’re on the go by keeping CREON in your purse, backpack, or at your work desk. You may also consider filling a pill case and taking it with you each day. Just remember to store CREON in a cool, dry place.

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Talk about your symptoms with your doctor

Keep track of any gastrointestinal (GI) symptoms you have after eating and discuss them with your doctor. Your doctor may need to adjust your dose.

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What can I eat with CREON?

Learn About
Diet & Lifestyle
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Tracking treatment can help your doctor see if your therapy is working for you

Treatment Tracker
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Your doctor will adjust your CREON dose to you and your needs

Learn About Dosing

Uses and Important Safety Information


CREON is a prescription medicine used to treat people who cannot digest food normally because their pancreas does not make enough enzymes due to cystic fibrosis, swelling of the pancreas that lasts a long time (chronic pancreatitis), removal of some or all of the pancreas (pancreatectomy), or other conditions.

Important Safety Information

  • CREON may increase your chance of having a rare bowel disorder called fibrosing colonopathy. The risk of having this condition may be reduced by following the dosing instructions that your doctor gave you.
  • Do not crush or chew CREON capsules or its contents, and do not hold the capsule or capsule contents in your mouth. Crushing, chewing, or holding the CREON capsules in your mouth may cause irritation in your mouth. Talk to your doctor or consult the CREON Medication Guide for how to take CREON if you have trouble swallowing capsules. Always take CREON with a meal or snack and enough liquid to swallow CREON completely. Take CREON exactly as your doctor tells you.
  • Tell your doctor right away if you have unusual or severe: stomach (abdominal) pain, bloating, trouble passing stool, nausea, vomiting, diarrhea, worsening of painful, swollen joints (gout), or allergic reactions including trouble with breathing, skin rashes, or swollen lips.
  • The most common side effects include: increased (hyperglycemia) or decreased (hypoglycemia) blood sugars, pain in your stomach area (abdominal area), frequent or abnormal bowel movements, gas, vomiting, dizziness, or sore throat and cough.
  • CREON and other pancreatic enzyme products are made from the pancreas of pigs, the same pigs people eat as pork. These pigs may carry viruses. Although it has never been reported, it may be possible for a person to get a viral infection from taking pancreatic enzyme products that come from pigs.

Refer to the CREON Medication Guide and Full Prescribing Information every time you refill your prescription because information may change. Tell your healthcare provider if you have any symptom or side effect that bothers you or that does not go away.

You are encouraged to report negative adverse effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

If you cannot afford your medication, contact

Reference: 1. CREON [package insert]. North Chicago, IL: AbbVie Inc.

  1. Reference:
  2. CREON [package insert]. North Chicago, IL: AbbVie Inc.

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